Cathartic Salts on Motility of Thiry-Vella Jejunal Loops.

Abstract

Summary

1. Isotonic Na₂SO₄ and isotonic MgSO₄ caused moderate stimulation of motility in Thiry-Vella jejunal loops; when prolonged, isotonic MgSO₄ caused depression of motility and tone. 2. Hypertonic solutions of NaCl, Na₂SO₄ or MgSO₄ caused depression of motility, with short periods of spasticity accompanied by symptoms of nausea. 3. Recovery after hypertonic NaCl or Na₂SO₄ was prompt, but after depression of motility by MgSO₄ recovery was slow. 4. Using a constant inflow pressure, flow bore an inverse relationship to motility. 5. Rate of contraction was unaffected by the agents employed.