Abstract
Summary
Evidence is presented which indicates that certain soluble sulfonamide-azo dyes interfere with the lytic activity of lysozyme upon M. lysodeikticus. One of these compounds, sulfathiazole-disazo-symmetrical-carbamide-2R acid, completely suppresses the lytic effects of the enzyme in a concentration of 1:10,000 of the drug. To our knowledge, these are the first sulfonamides found to exhibit anti-lysozyme properties.
Get full access to this article
View all access options for this article.