Abstract
Conclusions
1. Atropine causes excitement in the sea-star resulting in protraction of the tube feet and flexure of the rays. 2. Caffeine produces two types of effects, an early excitement followed by muscular rigor. 3. Picrotoxin causes acceleration of locomotion accompanied by active waving of the tube feet. 4. Caffeine and picrotoxin are mutually antagonistic in the sea-star, either drug being capable of reversing the effects of the .other. 5. The effects of atropine, caffeine, strychnine, and picrotoxin are reversible in the sea-star lbecause the animals will readily return to a normal state when placed in running sea water, showing no apparent muscular damage resulting.
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