Abstract
Summary
1. A positive nitrogen balance or nitrogen equilibrium may be maintained in protein-depleted dogs with a gelatin solution injected intravenously as practically the sole source of nitrogen.
2. Elevation of depressed blood plasma protein levels may obtain from intravenously administered gelatin as practically the sole source of nitrogen. The increase is apparently in the globulin fraction and represents to a large extent circulating gelatin. It was found that most of the gelatin used above in aqueous solution, or if added to plasma in vitro, precipitates with 2176 sodium sulphite (thus behaving like a “globulin”).
3. At least a portion of intravenously injected gelatin appears to be metabolized since there is a substantial increase in non-protein nitrogen excretion following injections.
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