Abstract
Summary
The addition of pure gamma globulin to normal spinal fluid produced a typically paretic colloidal gold curve. The degree of flocculation was proportional to the amount of gamma globulin added. Similar concentrations of the fraction containing alpha and beta globulins did not affect the colloidal gold reaction. Albumin inhibited colloidal gold flocculation. The addition of pure human albumin to the spinal fluid of a patient with paresis converted the paretic curve to normal. Since the gamma globulin is increased in the spinal fluid of patients with paresisll the paretic colloidal gold curve probably depends upon the relative increase in gamma globulin.
Get full access to this article
View all access options for this article.