Abstract
Conclusion
Neither in normal dogs receiving 10 mg doses of thyroxin intravenously, nor in intact dogs receiving phlorhizin, is there any parallelism between the blood iodine level and the basal metabolic rate. The former result conforms with expectations, since the blood is not the site of action of thyroxin. The latter finding is more unexpected, since the increase in metabolism which phlorhizin produces in dogs is very large and is abolished by thyroidectomy.
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