Abstract
Summary
The occurrence of protoporphyrin was studied in 133 sternal bone marrow specimens. Protoporphyrin was :mostregularly present in marrow samples containing predominately normoblastic young red blood cells.
Ninety-six sternal bone marrow specimens from 12 patients with Addisonian pernicious anemia before and after liver extract injection were obtained by serial sternal punctures at 24-hr intervals. The appearance of protoporphyrin was coincidental with the increase of immature red cells of normoblastic type in the marrow.
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