Abstract
Summary
1. Three paraquinones and one diorthoquinone were found to have well-defined blood pressure reducing properties in hypertensive rats. These compounds are 2, 5 dimethyl paraquinone (xyloquinone), 2 methyl 5 isopropyl paraquinone (thymo-quinone), trimethyl paraquinone and sodium rhodizonate. 2. This depressor effect is not associated with a febrile reaction and can be elicited by the oral as well as the subcutaneous route of administration. 3. These compounds have no effect on the blood pressure of normal non-hypertensive rats.
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