Abstract
Summary
Two dogs with occlusion of all pancreatic ducts showed extensive fatty changes of the liver about 12 months after operation. Two dogs with occlusion of the main pancreatic duct in which only a very small fraction of the pancreas had remained functioning showed no fatty changes of the liver after Tl/2 and 8]/2 months respectively. The development of fatty liver is evidently not due to a pancreatic hormone but due to the lack of the external pancreatic secretion and a very small fraction of the normal pancreas and its secretion seems to be sufficient to prevent it.
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