Abstract
Summary
The effect of certain split products of some carcinogenic azo dyes and related compounds on melanin formation was studied. It was observed that certain non-autoxidizable compounds such as p-aminoacetanilide, B-naphthylamine, p-aminobenzoic acid and sulfanilamide interfered with this reaction. When chemically related autoxidizable compounds (p-aminodimethylaniline, p-phenyl-enecliamine, methyl p-phenylenediamine and p-aminophenol) were used, the color changes in both tyrosine-tyrosinase and control solutions were similar. It is, therefore, difficult to interpret the action of these latter chemicals on melanin formation.
Get full access to this article
View all access options for this article.