Protective Action of Desoxycorticosterone Acetate and Progesterone in Adrenalectomized Mice Exposed to Low Temperatures

Abstract

Summary

By the use of a precold treatment injection schedule it has been demonstrated that desoxycorticosterone acetate at dose levels of 250 γ and 500 γ and progesterone at 500 γ prolongs the life of adrenalectomized mice subjected to low temperatures. Peanut oil at the dose level of 0.2 cc has been shown to possess a significant toxic action.