Abstract
Conclusions
The daily injection of 15 mg of progesterone for 10 days into sexually mature spayed rats increased the lactogen content of their pituitary glands, caused no significant increase in pituitary weight, and induced moderate development of the lobule-alveolar system and limited secretory activity of the mammary glands. The daily administration of 15 mg of progesterone + 33 γ of estrogen for 10 days caused extensive lobule-alveolar growth of the mammary glands. The secretory activity of the glands was somewhat greater than that observed following progesterone treatment. This treatment was less effective than estrogen but more effective than progesterone in increasing the lactogen content of the pituitary gland.
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