Abstract
Summary
A study was made of the effect of avidin on the growth of a number of bacterial species. A correlation was found between the biotin requirement of an organism and its growth-inhibition by avidin. In general, those organisms which have been found to require biotin as a growth-essential were inhibited by avidin, while those organisms which were found to synthesize biotin were unaffected. On the basis of this growth-inhibition by avidin, it is predicted that Cl. chauvei, Cl. botulinum, Cl. histolyticum, Cl. sporogenes, D. pneumoniae, L. casei ∊, L. acidophilus, and B. brevis, whose biotin requirements have not yet been established require biotin as a growth-essential.
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