Abstract
Summary
Three groups of male rabbits were injected with 3 different levels of estrone in order to determine whether estrogen could effect a simultaneous rise in the lactogenic hormone of the pituitary and blood stream. Assays of the pituitaries revealed that a considerable increase in lactogen was obtained, although the highest dosage of estrone (5000 I.U.) gave a smaller increase in lactogen than was secured with the two lower levels (500 and 1000 I.U.). Assays of the whole, untreated rabbit blood also showed that a definite increase in the release of lactogen into the blood stream was secured following the injection of estrone. These findings are believed to account for the initiation of lactation following suitable estrogen treatment.
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