Neuroinvasiveness of Poliomyelitis Virus in Relation to Vitamin D Nutrition. ∗

Abstract

Summary

Poliomyelitis developed in all of 8 rhesus monkeys following the injection of freshly passaged “M.V.” virus into their sciatic nerves. In 6 of these monkeys roentgenologic examinations of the long bones and determinations of inorganic and organic acid-soluble phosphorus in the blood just before inoculation gave no evidence of vitamin D deficiency. Indications of varying degrees of this deficiency were present in the other two animals.

There was no evidence that the capacity of poliomyelitis virus to invade the central nervous system along peripheral nerves depended on vitamin D deficiency.