Abstract
Conclusions
Intravenous administration of 0.1 g or more per kg of SSS produces death in normal dogs. 0.03 g per kg was found to be compatible with life. Injection of this quantity produced marked alteration in the usual course of the disease. Although serum-leukocyte mixtures did not always show complete abolition of blood pneu-mococcidal power, the presence of this substance in the blood and tissues resulted in overwhelming bacteremia, inability of the dog to localize infection and impaired phagocytosis in the pulmonary lesion.
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