Abstract
Summary
A substance which acted destructively upon the myelin sheaths of rat spinal cord could be demonstrated in the urines of patients suffering from disseminated sclerosis. It was more frequently observed during periods of exacerbations than during periods of remissions. Similar myelolytic substances were also observed in cases of post-encephalitic Parkinsonism, but they were absent in syphilis and in other diseases of the central nervous system. This myelolytic substance could be isolated from the concentrated urines by extraction with dioxane.
Get full access to this article
View all access options for this article.