Abstract
Summary
1. The RBC and hemoglobin content of normal rats show higher values than those of normal females. 2. Following castration, the RBC and hemoglobin contents of the males drop, while those in the females rise. 3. Injections of estradiol into castrated females, and testosterone into castrated males produce, respectively, a drop and rise in RBC and hemoglobin. 4. Bone marrow studies indicate that androgens stimulate and estrogens inhibit erythro-cytopoiesis. 5. Additional support is thus given to the sex hormone explanation of the normal sex difference in RBC reported for many species of animals.
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