Abstract
Conclusions
1. Sulfanilamide by oral administration in dosage of 0.1 g per kilo of weight, twice daily for 10 to 14 doses, had no appreciable effect upon the evolution and clinical course of experimental vaccinia of rabbits. 2. Under the circumstances it is unlikely that sulfanilamide has any effect upon the virus of smallpox, although its administration may be helpful in the treatment of smallpox and generalized vaccinia by reducing secondary staphylococcus or streptococcus infections of the vesicles.
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