Abstract
Conclusions
2-(Sulfanilamido)-5-ethyl-4-thiazolone (sulfaethyl-thiazolone) has less antistreptococcic activity and approximately the same antipneumococcic activity as sulfapyridine. Its antistaphylococcic activity is of the same order as that of sulfathiazole and sulfadiazine.
Sulfadiazine produces urolithiasis medicamentosa capable of causing death by acute suppression of urine in mice and rats, whereas sulfaethylthiazolone is free of this defect, but may cause fatal anemia.
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