Abstract
Summary
Pregneninolone alone and injected subcutaneously with estrone into castrate virgin female mice caused the development of the lobule-alveolar system of their mammary glands, having a property similar to progesterone in this respect. The injection of estrone with the pregneninolone enhanced this activity of the pregneninolone by five times. Pregneninolone has one-half the activity of progesterone in stimulating mammary lobule-alveolar growth when both are injected with estrone.
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