Abstract
Summary
In tests made on 41 normal young White Carneau pigeons daily injections of 1-60 units of insulin during 10 hours to 10 days enlarged the adrenals, produced mitosis and cellular activity. These cytological effects were more pronounced in cortical cells than in medullary cells. Wholly comparable effects were produced in the adrenals of 16 additional birds previously deprived of their anterior pituitary glands. The cytological changes in the cortex following insulin are identical with those induced by adrenotrophic pituitary extracts. Food consumption of the test animals and of 73 controls was regulated at different and definite levels. The relation of these results to the alarm reaction and to the rôle of the adrenals in carbohydrate regulation is discussed.
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