Abstract
Conclusions
A synthetic, chemically-defined medium has proved satisfactory for the study of the bacteriostatic effect of the sulfonamide compounds upon staphylococci. Sulfathiazole and sulfadiazine have a definitely greater inhibitory effect upon growth compared to sulfapyridine and sulfanilamide, with sulfathiazole superior to sulfadiazine. While p-aminobenzoic acid inhibits this bacteriostatic action of all the compounds studied, the greater the effect of a compound upon growth of Staphylococci, the less inhibitory is p-aminobenzoic acid against this action of the compound.
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