Abstract
Summary
Angiotonin, when applied directly or administered intravenously produced transient vasoconstriction with cessation of activity of the glomerular circulation for about one minute. This was followed by moderate engorgement of the glomeruli which lasted about 8 minutes. When angiotonin was administered subcutaneously, moderate engorgement of the glomeruli was produced without an initial cessation of glomerular circulatory activity. With successive administrations of angiotonin, the blanching effect disappeared but the glomerular engorgement was observed consistently.
Renin had no detectable effect on the renal circulation in the frog.
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