Abstract
Summary
In normal rabbits, the cholesterol content of whole blood is distinctly higher than that of serum or oxalated plasma prepared from the same blood sample. The blood cells of normal rabbits contain almost 2 1/2 times as much cholesterol as an equal volume of plasma. In cholesterol-fed rabbits, the cholesterol content of whole blood is definitely lower than that of serum or oxalated plasma. Cholesterol feeding does not influence the cholesterol content of the blood cells. Humans are unlike normal rabbits but simulate cholesterol-fed rabbits in the distribution of this sterol between cells and plasma. Cholesterol feeding produces an anemia in rabbits, an observation previously noted in the guinea pig by Okey and Greaves. 7
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