Abstract
Summary
When dogs were placed on a diet deficient in nicotinic acid, the addition of nicotinic acid corrected the deficiency, while the addition of nicotinic acid and sulfapyridine failed to do so. When raw liver and sulfapyridine were added to the diet, the deficiency disappeared. It seems possible, but not proven, that sulfapyridine inhibits the action of nicotinic acid but not of preformed coenzymes.
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