Abstract
Conclusions
Neither alpha-tocopherol nor testosterone-propionate in the doses given had any effect on the creatine-creatinine excretion in the cases of amyotonia congenita and progressive muscular dystrophy studied. This should not be interpreted as failure of these substances as therapeutic agents. It indicates, however, that alpha-tocopherol does not have the same inhibitory effect on creatinuria in neuro-muscular disturbances in human beings as in the nutritional muscular dystrophy in rabbits. This suggests a fundamental difference between nutritional muscular dystrophy in rabbits and progressive muscular dystrophy, amyotonia congenita and similar neuromuscular disturbances in human beings.
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