Abstract
Summary
Isoandrosterone, androsterone, and etiocholanol-3(α)-one-17 have been isolated from the urine of a woman suffering from virilism. No dehydroisoandrosterone has been found.
While this paper was in press Pearlman 7 reported the isolation of isoandrosterone from the urine of normal women and of patients with cancer. The yield which is given only for normal female urine is appreciably lower than that obtained from this case of virilism.
The author is greatly indebted to Professor G. F. Cahill, Columbia University, for permission to report his clinical observations, to Professor O. Wintersteiner, Columbia University, for his helpful advice, and to Dr. H. H. Darby, Columbia University, for the bio-assay data and for arranging for the urine collections.
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