Abstract
Conclusions
I. Potentials across the skin in the intact frog remain remarkably constant. Manipulation of electrodes or position of the frog has little influence on potential readings. II. Destruction of the nervous system causes a sudden decrease in skin potential. The average decrease in potential after brain and spinal cord destruction is approximately 25% in each case. III. Following intraperitoneal injection of strychnine sulphate into the intact frog there is an increase in skin potential for approximately 15 minutes, after which there is a gradual return to normal. IV. Alterations in circulation by removal of the heart causes no appreciable change in skin potential.
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