Abstract
Summary
Dental plaque material was suspended in glucose solution and incubated with the quaternary ammonium wetting and detergent compound, alkyldimethylbenzyl ammonium chloride. One part of this compound in 3,000 (approximately M/1000) completely inhibited the production of acid by the plaque material.
In another type of experiment, a 1:500 solution of the detergent was applied to the plaque material in situ for 2 minutes. The plaque material was removed 10 minutes later, and did not produce appreciable quantities of acid when it was then incubated in glucose solution.
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