Abstract
Summary
The dystrophy that almost invariably appears toward the end of the lactation period in the suckling young of vitamin E-low mothers can be prevented by the administration of 10 mg of alpha-tocopherol to the mother on the day of littering or the feeding of 1 mg daily to the young from day 10 or 3 mg from day 15. The administration of 3 mg of alpha-tocopherol daily from day 18 was ineffective. The following compounds related chemically to alpha-tocopherol were tested for anti-dystrophic activity and found inactive: 2,2,5,7,8-penta-methyl, 6 hydroxy chromane, phytol, gamma lactone and vitamin K1.
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