Abstract
Conclusions
The cotton rat was found relatively refractory to anaphylactic shock. In this respect it resembles the ordinary laboratory rat. Low titered precipitins occurred in 3 of the 9 serums tested after sensitization. The minimal lethal dose of histamine intravenously was approximately 0.8 mg per 100 g for the cotton rat. This is 15 times the quantity required to kill a guinea pig, but is 100 times less than that which has been reported lethal for the rat.
Get full access to this article
View all access options for this article.