Bioassay of Water-Soluble Antihemorrhagic Compounds by Intravenous Administration. ∗

Abstract

Summary

Using intravenous administration it has been found that on a molecular basis the potencies of all the compounds with the exception of the disulfate are approximately equal to that of the standard, Z-methyl-l,4-naphthoquinone. The disul fate is about onethird as potent on a niolecular basis, but owing to the much larger molecular weight its activity per milligram is somewhat less than one-sixth that of 2-methyl-1, 4-naphthoquinone.