Abstract
Conclusions
1. The rabbit is able to produce an antiserum which counteracts the pressor effect of dog renin. 2. The antiserum for dog renin appears to diminish the pressor response to rabbit renin.
3. This antiserum has no effect on the pressor action of pituitrin.
4. The dog appears able to produce an antiserum to hog renin. 5. The active principle of the antiserums (antirenin) is most likely a non-precipitating antibody or possibly an antihormone. 6. Studies are now in progress to determine the value of antirenin in the therapy of experimental renal hypertension and also in the elucidation of the possible pathogenetic rôle of renin in this form of hypertension.
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