Abstract
Conclusions
Sulfathiazole is an effective bacteriostatic and bactericidal agent against S. aureus when added to defibrinated whole blood in vitro. Concentrations between 2.5 and 5 mg/100 cc are necessary to obtain the maximal effect. Comparison of this drug with sulfamethylthiazole, sulfanilamide, and sulfapyridine show it to be somewhat superior in the experiments reported.
We wish to thank The Squibb Institute of Medical Research for the supply of sulfathiazole and The Department of Medical Research of the Winthrop Chemical Company for the supply of sulfamethylthiazole used in this investigation.
We wish to thank Miss Marjorie Jewell and Miss Eleanor Fleming for technical assistance.
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