Abstract
Summary
Comparing the gonadotropic response of the organism to subcutaneous or intraperitoneal administration of pregnancy urine prolan the following results were secured: (1) If the minimum dose is split up into 6 portions intraperitoneal and subcutaneous administration are equally effective. (2) If the minimum dose is split up into 3 portions the intraperitoneal route is approximately half as effective as the subcutaneous one. (3) If the minimum dose is given in one injection the intraperitoneal administration is about 1/10 as effective as subcutaneous. (4) Using the subcutaneous standardization method with minute doses as e.g., 1 RU (estrous effect) the gonadotropic effect of 6 subthreshold doses is less marked than that of one single threshold dose.
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