Abstract
Conclusions
(1) Keto-reacting substances are present in dogs' bile and can be quantitatively determined. (2) The output of keto-reacting substances is increased slightly when unoxidized bile acids are fed. (3) When oxidized bile acids or ketocholanic acids are administered orally, the output of keto-reacting substances in the bile is markedly increased. By assuming that the increase over the control output is due to the ketocholanic acid fed, one may calculate the recovery in the bile of the ketocholanic acid administered.
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