Abstract
Summary and Conclusions
It appears from these studies that, by means of the implantation of crystals of a-estradiol and a-estradiol benzoate, it is possible to achieve a strikingly more prolonged inhibition of the hypophysis in post-menopause and ovariectomized women than can be obtained by the injection of comparable amounts of estrogenic hormone in solution in oil. These findings are in accord with the clinical observations of the prolonged therapeutic effect resulting from the implantation of the estrogen crystals.
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