Abstract
Conclusions
Based upon weight responses evoked in the end organs of castrated male rats, the results obtained with androgens, percutaneously administered, indicate the effectiveness to follow the descending order—methyl-testosterone, free testosterone and t-propionate (lowest), although the differences between the first two substances are not great. It is further suggested that androgens carried in a tegin base are more effective than when carried in a lanol base, since end organ weights were greater in 30 of the 32 compared pairs. With all dosages the histologically indicated secretory normality was apparent for both ventral prostates and seminal vesicles.
I wish to acknowledge grateful appreciation to Dr. Carl R. Moore for directing this investigation, to Dr. Dorothy Price for friendly interest and assistance, and to Mrs. Dorothy Plagge for aid with operations.
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