Abstract
Conclusions
The effectiveness of estrogens in inhibiting lactation in the rat can be increased through simultaneous administration of a gonadotropic principle from pregnant women's urine. Many cells in mitoses are observed in the mammary gland parenchyma of rats so treated. It is believed that this is the mechanism of the inhibitory action of these hormones on lactation. That is, one would not expect a proliferating gland to secrete as efficiently as a non-proliferating gland. The administration of an estrogen plus a gonadotropic principle to lactating rats augments the lactogen content of the pituitary gland.
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