Abstract
Conclusions
1. Specific antisera have been prepared for the proteins of malignant tissue. 2. There is a suggestion of a relative anatomic specificity of carcinomatous tissue, as a greater number of positive reactions occur with autolysates of the homologous tissue and with sera of cases having the same type of malignancy. 3. These precipitins for the proteins of malignant tissue show promise as diagnostic aids. A high percentage of sera from patients with malignant tumors react positively. The higher percentages of positive reactions were obtained in cases where the malignant growth had the same anatomic location as the tumor from which the anti-serum had been prepared. 4. Our preliminary results indicate that possibly these precipitins are species-specific, because antisera for rat-tumors do not react with autolysates of human carcinoma and vice-versa.
Get full access to this article
View all access options for this article.