Abstract
Conclusions
(1) A 3-day curative technic for the biological assay of the antihemorrhagic factor has been developed. If a vitamin K standard is run with each group of chicks and certain precautions in the procedure are observed, the assay is quantitative within the limits of error for a biological assay. (2) The vitamin K activity of a compound varies significantly with the solvent and the method of administration. (3) The vitamin K activity of 2-methyl-1,4-naphthoquinone and of 2-methyl-1,4-naphthoquinhydrone is approximately the same as the natural vitamin K1 on a molar basis.
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