Abstract
Summary
Increase of weight in the adrenals of the normal immature (1.9 mo.) pigeon, and degree of maintenance of adrenal weight during 10 days following hypophysectomy in the pigeon, and also cytological evidence of stimulation in their cortical cells, are found to agree satisfactorily with Moon's method of assay of adrenocorticotropin in 21-day rats. As tested by these 3 methods the ability of pituitary extracts to stimulate cortical tissue is independent of their prolactin, FSH and thyrotropin potencies. Gamone stimulates both cortical and medullary tissue in both normal and hypophysectomized pigeons. Estrone stimulates cortical tissue at least in intact birds. Thyroxine, plus vitamin supplements, gave evidence of ability to stimulate cortical tissue in hypophysectomized pigeons.
Get full access to this article
View all access options for this article.