Abstract
Conclusions
The occurrence of free polysaccharide in the blood of pneumonic patients is not uncommon. Its presence is generally indicative of a severe infection, with usually fatal outcome. It would appear that sulfapyridine alone may be ineffective in the control of those pneumococcic infections which are accompanied by the production of sufficient polysaccharide to reach relatively high concentrations in the blood stream, but that it may be effective in such instances if it is combined with the administration of sufficient type-specific antibody. The observations reported suggest that sulfa-pyridine alone may control pneumococcic infections provided there is not too much antigen present in the blood, and some specific antibody is produced.
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