Abstract
Summary
1. A method of preparation of “uveal-tissue-toxin” is described. 2. Repeated intracutaneous injections with heterologous (bovine) uveal-tissue-toxin produced simultaneous sensitization to heterologous (swine), homologous, and autogenous uveal pigment in 6 out of 22 rabbits. 3. Similar sensitizing injections with homologous uveal-tissue-toxin produced no sensitization to uveal pigment in any of the 11 rabbits used. 4. Repeated injections of uveal-tissue devoid of staphylotoxin produced no sensitization to uveal pigment. 5. The criterion of hypersensitivity was based upon the histologic cellular reaction observed in tissues excised 2 weeks after the injection.
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