Abstract
The following conclusions were reached as the results of the analysis according to the Wakeman-Kossel method for the determination of hexon bases of the normal and necrotic livers of dogs and horses in various stages of necrosis and of the same after autolysis for varying lengths of time.
Necrosis was induced in the case of the dog by means of the injection of hæmotoxic immune sera and in the horses by injections of bacterial toxins.
1. The dry solid content of the (a) scattered and of the (b) diffusely necrotic liver tissue showed no variation from that of the normal.
2. The nitrogen of the dry substance averaged 11 per cent, in the normal liver, 21.7 per cent, in those with scattered necroses (increase 95.4 per cent.) and 12.65 per cent. in the diffusely necrotic (increase 5.3 per cent).
3. In the cases of scattered focal necroses the nitrogen precipitable by phosphotungstic acid after acid hydrolysis formed 11.3 per cent, and in the diffused necroses 30 per cent, of the total nitrogen as against 15 per cent, for the normal; a decrease of 25 per cent, for the first and an increase of 100 per cent, for the more advanced type of necrosis.
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