Abstract
A dog with an Eck fistula was maintained in nitrogenous equilibrium on a diet consisting of cracker meal, plasmon and lard, and the following chemical observations were made:
1. The output of uric acid was compared with that of a normal dog. An increase in the output was noted.
2. The influence of nuclein, nucleic acid and of adenin on the uric acid elimination was studied. It was observed that all these substances caused an increase in the uric acid elimination.
3. The fate of thymin ingested with the food was investigated. The greater part of the ingested thymin was recovered from the urine.
4. An attempt was made to find thymin in the urine of the same dog after feeding on nuclein and on nucleic acid. The endeavor was not successful.
5. The influence of a diet containing a small proportion of protein but abundant in calories was studied. It was noticed that this diet occasioned an increase in the uric acid output.
6. The influence of fasting on the uric acid output was observed. It was noted in the course of the fast that the uric acid elimination was above the normal.
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