Effect of Sorbitol and Sucrose on Cerebrospinal Fluid Pressure and Urine Output

Abstract

Summary

Parallel experiments have been carried out on 9 pairs of dogs. 50% sorbitol, in a dosage of 2.5 cc/kg, injected intravenously at a rate of 7 cc/min causes a more marked and protracted fall in cerebrospinal fluid pressure, and a greater diuresis, than does an equivalent amount of sucrose.