Abstract
Conclusions
Physostigmine and strychnine administered to normal rats in doses of 0.10 and 0.52 mg per kg respectively, exerted a statistically significant, hyperglycemic synergism. The synergistic action increased the mean of the maximal hyperglycemia of strychnine 330% and the sun of the means of the maximal actions of physostigmine and strychnine 47%. The quantities of the drugs employed did not produce objectionable systemic effects. After demedullation of the adrenals the drugs lost their hyperglycemic action.
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