Chemical Composition of Transverse Metaphyseal Bands Produced in Growing Bones by Phosphorus Ingestion

Abstract

Conclusions

1. The bone in the phosphorus bands produced in the metaphyses of growing long bones by the ingestion of phosphorus is of normal chemical composition. 2. The increased density represents deposition of radio-opaque salts in greater amount per unit of tissue calcified, since calcification and ossification have continued unchecked while the cartilaginous growth was inhibited. 3. This observation constitutes additional evidence that the zones of increased density in metaphyses of growing bones, produced by ingested phosphorus, are in fact “growth arrest lines.”